|
|
Article: Research from China University yields new data on medicinal chemistry.
- Article from:
- Chemicals & Chemistry
- Article date:
- November 13, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
"18 beta-Glycyrrhetinic acid (GA) is the active component in licorice root. Recent study has shown that GA exhibits many pharmacological activities," scientists writing in the journal Medicinal Chemistry Research report.
"Here a new derivative of GA, biotinylated GA (BGA), was synthesized by introducing the biotin to the C-29 carboxyl of GA, and its antitumor effects were confirmed through tests on mouse B16 melanoma cells and BEL 7402 human hepatocarcinoma cells. At the same time, it is shown that the biotin group in BGA has no influence on the antitumor effects of GA," wrote J.H. Shi and colleagues, China University.
The researchers concluded: "Then ...