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Article: Scientists at University of Florence report research in physical chemistry.
- Article from:
- Chemicals & Chemistry
- Article date:
- November 13, 2009
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According to a study from Florence, Italy, "Spin-labeled sulfonamides incorporating TEMPO moieties showed efficient activity as inhibitors of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1) and, in particular, of the physiologically relevant isoenzymes hCA II, hCA IX, and hCA XIV. Here we report I detailed analysis of this class of inhibitors by means of ESR and X-ray crystallography, in comparison with inhibition tests against all mammalian CA isoforms, CA I-XIV."
"Local dynamics and Structure were manifested in the ESR signal through modulation of internal magnetic anisotropies. Analysis and fitting of the ESR spectra of several spin-labeled sulfonamides ...
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Article: Study findings from University of Florence provide new ...
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... ... Evolution. Journal of Physical Chemistry B, 2009;113(10 ... Baglioni, University of Florence, Dept. of Chemical ... Fiorentino, I-50019 Florence, Italy. Publisher ... for the Journal of Physical Chemistry B is: American Chemical ... Physics, University of Florence. This article was ...
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