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Article: Protective CD4(+) and CD8(+) T Cells Against Influenza Virus Induced by Vaccination with Nucleoprotein DNA.
- Article from:
- Vaccine Weekly
- Article date:
- September 7, 1998
CopyrightCOPYRIGHT 1998 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Ulmer, J.B.; Fu, T.M.; Deck, R.R.; Friedman, A.; Guan, L.M.; Dewitt, C.; Liu, X.; Wang, S.; Liu, M.A.; Donnelly, J.J.; Caulfield, M.J. "Protective CD4(+) and CD8(+) T Cells Against Influenza Virus Induced by Vaccination with Nucleoprotein DNA." Journal of Virology, July 1998;72(7):5648-5653.
According to the authors' abstract of an article published in Journal of Virology, "DNA vaccination is an effective means of eliciting both humoral and cellular immunity, including cytotoxic T lymphocytes (CTL). Using an influenza virus model, we previously demonstrated that injection of DNA encoding influenza virus nucleoprotein (NP) induced major histocompatibility complex ...