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Article: Research in the area of atherosclerosis reported from University of Amsterdam.(Report)
- Article from:
- Biotech Week
- Article date:
- November 18, 2009
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"Transglutaminases play an important role in vascular smooth muscle cell-induced calcification in vitro. In this study, we determined whether these enzymes are also involved in human atherosclerotic calcification using nine carotid artery specimens obtained at endarterectomy," scientists writing in the American Journal of Pathology report (see also Atherosclerosis).
"Sections of the carotid artery specimens were registered to micro-computed tomography images and stained for tissue-type transglutaminase, plasma transglutaminase factor XIIIA (FXIIIA), the N-epsilon(gamma-glutamyl)lysine cross-link, and the macrophage marker CD68. Ex vivo micro-computed tomography ...