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Article: New findings from University of Parma describe advances in herpes virus.
- Article from:
- Blood Weekly
- Article date:
- November 19, 2009
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According to a study from Parma, Italy, "Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with a Worldwide distribution in cattle and is often isolated from the uterus of animals with postpartum metritis or pelvic inflammatory disease. Virus strain adaptation to an organ, tissue or cell type is an important issue for the pathogenesis of disease."
"To explore the mechanistic role of viral strain variation for uterine disease, the present study aimed to develop a tool enabling precise genetic discrimination between strains of BoHV-4 and to easily manipulate the viral genome. A strain of BoHV-4 was isolated from the uterus of a persistently infected cow and ...