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Article: Research results from University of Lyon update knowledge of cell proliferation.
- Article from:
- Cancer Weekly
- Article date:
- November 17, 2009
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According to recent research published in the journal Biology of the Cell, "Information. miRNAs (microRNAs) are a class of non-coding RNAs that inhibit gene expression by binding to recognition elements, mainly in the 3' UTR (untranslated region) of mRNA. A single miRNA can target several hundred mRNAs, leading to a complex metabolic network. miR-16 (miRNA-16), located on chromosome 13q14, is involved in cell proliferation and apoptosis regulation; it may interfere with either oncogenic or tumour suppressor pathways, and is implicated in leukaemogenesis."
"These data prompted us to search for and validate novel targets of miR-16. In the present study, by using a ...
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