Article: Reports from A.O. Verkerk et al highlight recent research in pacemakers.

According to recent research published in the journal Heart Rhythm, "Omega-3 polyunsaturated fatty acids (omega 3-PUFAs) from fish oil (FO) reduce heart rate in humans. The mechanism underlying this cardio protective effect of FO is unknown."

"We studied the effects of an FO diet on heart rate, pacemaker activity, and pacemaker current (I-f) in sinoatrial node (SAN) cells. Rabbits were fed a diet enriched with 2.5% (w/w) FO or 2.5% high oleic sunflower oil (50) as control for 3 weeks. Heart rate was measured in Langendorff-perfused hearts. Pacemaker activity and I-f were recorded using the perforated patch-damp technique in isolated SAN cells. In SAN cells, the ...

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