Article: Research conducted at M. Faiyaz-Ul-Haque and co-authors has provided new information about autoimmune disease genetics.(Report)

Data detailed in 'Novel and recurrent mutations in the AIRE gene of autoimmune polyendocrinopathy syndrome type 1 (APS1) patients' have been presented. "Autoimmune polyendocrinopathy syndrome type 1 (APS1) is characterized by the presence of at least two out of three clinical features, which include Addison's disease, hypoparathyroidism, and chronic mucocutaneous candidiasis. This disorder is caused by mutations in the AIRE (autoimmune regulator) gene," scientists in Riyadh, Saudi Arabia report (see also Autoimmune Disease Genetics).

"While several AIRE mutations have been described in APS1 patients of various ethnic origins, the genetic cause of APS1 in Arab ...

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