Article: Investigators at Georgia State University have published new data on physical chemistry.(Report)

According to recent research from the United States, "Hairpin nucleic acids are frequently used in physical studies due to their greater thermal stability compared to their equivalent duplex structures. They are also good models for more complex loop-containing structures such as quadruplexes, i-motifs, cruciforms, and molecular beacons."

"Although a connecting loop can increase stability, there is little information on how the loop influences the interactions of small molecules with attached base-paired nucleic acid regions. In this study, the effects-of different hairpin loops on the interactions of A/T specific DNA minor groove binding agents with a common ...

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