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Article: Studies from Autonomous University provide new data on Bacillus subtilis.
- Article from:
- Genomics & Genetics Weekly
- Article date:
- November 20, 2009
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According to recent research from Madrid, Spain, "Members of groups 1 (e.g. 29) and 2 (e.g. Nf) of the 29 family of phages infect the spore forming bacterium Bacillus subtilis."
"Although classified as lytic phages, the lytic cycle of 29 can be suppressed and its genome can become entrapped into the B. subtilis spore. This constitutes an alternative infection strategy that depends on the presence of binding sites for the host-encoded protein Spo0A in the 29 genome. Binding of Spo0A to these sites represses 29 transcription and prevents initiation of DNA replication. Although the Nf genome can also become trapped into B. subtilis spores, in vivo studies showed ...