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Article: Research from Kyoto University, Medical Department reveals new findings on genetics.
- Article from:
- Genomics & Genetics Weekly
- Article date:
- November 20, 2009
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According to a study from Kyoto, Japan, "Bloom syndrome caused by inactivation of the Bloom DNA helicase (Blm) is characterized by increases in the level of sister chromatid exchange, homologous recombination (HR) associated with cross-over. It is therefore believed that Blm works as an anti-recombinase."
"Meanwhile, in Drosophila, DmBlm is required specifically to promote the synthesis-dependent strand anneal (SDSA), a type of HR not associating with cross-over. However, conservation of Blm function in SDSA through higher eukaryotes has been a matter of debate. Here, we demonstrate the function of Blm in SDSA type HR in chicken DT40 B lymphocyte line, where Ig ...
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Article: Research from Kyoto University provides new data on ...
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... ... Journal of Biological Chemistry, 2009;284 ... K. Ueda, Kyoto University, Institute ... Journal of Biological Chemistry is: American ... Supplement, Biological Chemistry, Metabolism, Kyoto University. This article ...
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