Article: Study results from Mayo Clinic update understanding of hepatitis C virus.

According to a study from the United States, "Many patients with chronic hepatitis C have not responded to therapy with pegylated interferon plus ribavirin. To evaluate use of peginterferon-alpha 2a plus ribavirin to re-treat nonresponders to peginterferon-alpha 2b plus ribavirin."

"Randomized, parallel-group trial conducted between September 2003 and February 2007. and researchers were not blinded to intervention assignment. Random assignment was centralized, computer-generated, and stratified by geographic region, hepatitis C virus (HCV) genotype, and histologic diagnosis. 106 international centers. 950 nonresponders to 12 or more weeks of therapy with ...

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