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Article: New research on translational research from G.D. Kitsios and co-authors summarized.
- Article from:
- Science Letter
- Article date:
- November 17, 2009
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According to recent research from the United States, "The advent of the first wave of genome-wide association studies (GWAS) provided a new conceptual framework in the search for variants underlying common disorders: a massive scan of the genome, free from underlying assumptions for biological or positional candidate loci, genes, and variants. Thus, GWAS have been labeled as a 'free'' or ''agnostic'' approach, overcoming the obstacles imposed by the incomplete understanding of disease pathophysiology."
"Despite undisputable successes of the genome-wide approach, the available output from GWAS explains only a fraction of disease heritability. Although strategies ...