Article: Similar molecular tweaks led both a shrew and a lizard to produce venom.

Biologists have shown that independent but similar molecular changes turned a harmless digestive enzyme into a toxin in two unrelated species -- a shrew and a lizard -- giving each a venomous bite.

The work, described this week in the journal Current Biology by researchers at Harvard University, suggests that protein adaptation may be a highly predictable process, one that could eventually help discover other toxins across a wide array of species.

"Similar changes have occurred independently in a shrew and a lizard, causing both to be toxic," says senior author Hopi E. Hoekstra, John L. Loeb Associate Professor of the Natural Sciences in Harvard's ...

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