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Article: Research by E. Varghese and colleagues in pediatrics provides new insights.
- Article from:
- Pediatrics Week
- Article date:
- November 21, 2009
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According to a study from Manipal, India, "Epidural and other regional blocks are performed in children under general anesthesia; the response to a 'test dose' may be altered during administration of general anesthetics. Limited data is available describing changes in electrocardiogram, blood pressure and heart rate (HR) following unintentional intravascular injection of a lidocaine-epinephrine-containing test dose, under sevoflurane anesthesia in children."
"Sixty-eight children undergoing elective surgeries under sevoflurane anesthesia were administered 0.1 ml center dot kg-1 of 1% lidocaine with epinephrine 0.5 mu g center dot kg-1 or normal saline ...