|
|
Article: Roles of serum vitronectin and fibronectin in initial attachment of human vein endothelial cells and dermal fibroblasts on oxygen- and nitrogen-containing surfaces made by radio frequency plasmas
- Article from:
- Biomedical Materials
- Article date:
- January 1, 1995
CopyrightCOPYRIGHT 1995 International Newsletters. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
The initial attachment and spreading of cultured fibroblasts and endothelial cells onto films deposited using nitrogen-containing gases were equivalent to that onto films deposited using oxygen-containing monomers, but there were differences in the mechanism of attachment. With films deposited using oxygen -containing monomers, the initial attachment and spreading of endothelial cells failed when the medium contained 15% serum from which both fibronectin (Fn) and vitronectin (Vn) had been removed. Similarly, initial attachment and spreading of endothelial cells onto films deposited using oxygen-containing monomers were reduced by 62-86% when the cells were seeded in medium ...