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Article: HIV-1 Modified Assays Screen Large Numbers of Serum Samples
- Article from:
- Blood Weekly
- Article date:
- June 22, 1998
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It is possible to use certain assays efficiently in screening large numbers of serum samples for the presence of HIV, study results show.
To detect antibody-negative HIV-1 RNA positive samples among sera sent to microbiological laboratories, Pierre-Alain Morandi of Switzerland's Geneva University Hospital and colleagues developed two modified formats of a commercially available assay for the analysis of pooled sera ("Detection of Human Immunodeficiency Virus Type 1 (HIV-1) RNA in Pools of Sera Negative for Antibodies to HIV-1 and HIV-2," Journal of Clinical Microbiology, June 1998;36:1534-1538)).
The researchers prepared a total of 234 pools from 10,692 ...