Article: ARE HEROIN ADDICTS BORN, MADE OR BOTH? GENETIC ANALYSIS OF ENDORPHIN RECEPTOR VARIATIONS REVEALS BASIS OF DRUG ABUSE PRONENESS

By David N. Leff Science Editor Marathon runners will tell you that after running a certain number of the 26.4 miles in the footrace, they feel very exhausted, but press on.

Molecular geneticist Lei Yu, of the University of Cincinnati (Ohio) College of Medicine, puts it this way: "People who do regular running experience this second-wind effect. They feel they are hitting a wall; they can't push themselves further. But if they persist - keep running - after a while they will feel what's called an "endorphin high" - a very nice sensation, as if the fatigue is gone; as if they can run on forever."

Whence this blissful new spurt of energy?

"Sports ...

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