Article: Postmenopausal Hormone Therapy Does Not Decrease Risk of Heart Attack And Coronary Death in Women With Previous Heart Disease

PHILADELPHIA, Aug. 18 /PRNewswire/ -- A major clinical trial led by University of California, San Francisco (UCSF) researchers and colleagues at 18 medical centers in the United States found that estrogen plus a progestin did not decrease the overall risk of heart attack and coronary death among postmenopausal women with previous heart disease.

The study, published August 19, 1998 in The Journal of the American Medical Association, reported that the hormone therapy appeared to increase the risk of heart attack in the first year of treatment and then to decrease it after 2 years of treatment. The two effects balanced out, so that the number of women who had heart ...

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