Article: Companies Join To Provide Drug Discovery Solutions

Pharmaceutical companies are looking increasingly to outsource their drug discovery research, both to complement their own efforts and to gain access to proprietary technologies that will help them accelerate the discovery process. One focus of this thrust concerns the development of leads - novel biologically active compounds that have affinities for selected enzyme or receptor biological targets, compounds that could serve as bases for drug candidates.

Historically, the main sources of leads have been natural products isolated from plant, animal, or fermentation materials. There is a great diversity of candidates here; however, this often is a disadvantage because ...

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