Article: US DEPT OF HHS: Platinum-based chemotherapy for ovarian cancer carries increased risk of leukemia.

M2 PRESSWIRE-3 February 1999-US DEPT OF HHS: Platinum-based chemotherapy for ovarian cancer carries increased risk of leukemia (C)1994-99 M2 COMMUNICATIONS LTD

RDATE:290199

A report in the Feb. 4 issue of the "New England Journal of Medicine"* concludes that women who were treated for ovarian cancer with platinum-based chemotherapy (cisplatin or carboplatin) have a two to eight times greater chance of developing leukemia. Larger doses and longer treatments resulted in higher risks of acute and/or myeloid leukemia.

Although a number of small case reports have linked platinum-based chemotherapy regimens to secondary leukemia, this is the first ...

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