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Article: Role of Faulty DNA Repair in Breast Cancer Discovered.
- Article from:
- Gene Therapy Weekly
- Article date:
- April 26, 1999
CopyrightCOPYRIGHT 1999 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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(CW HENDERSON PUBLISHER www.newsfile.com) -- A research team at the University of Pittsburgh Cancer Institute and Magee-Womens Hospital has uncovered a pivotal role for problems with DNA repair in breast cancer.
The finding could help explain why most early-stage breast cancers respond to available treatments and why advanced tumors thrive despite aggressive therapy.
The report provides the first evidence that cells from early-stage breast cancers fail to repair DNA like normal cells through nucleotide excision repair (NER). The details were reported at a mini-symposium on April 13, 1999, at the annual meeting of the American Association for Cancer ...