Article: Guidelines for the Optimal Use of Muromonab CD3 in Transplantation.

Monoclonal Antibodies

Tenberge, I.J.M.; Parlevliet, K.J.; Raasveld, M.H.M.; Buysmann, S.; Bemelman, F.J.; Schellekens, P.T.A. "Guidelines for the Optimal Use of Muromonab CD3 in Transplantation." Biodrugs, April 1999;11(4):277-284.

(CW HENDERSON PUBLISHER www.newsfile.com) -- According to the authors' abstract of an article published in Biodrugs, "Muromonab CD3 (OKT3), the murine anti-CD3 monoclonal antibody (mAb) of the IgG-2a class, directed against the CD3 molecule on the surface of human T cells, has proven to be a powerful immunosuppressive agent in solid organ transplantation and has been shown to be superior to high-dose steroids as first-line ...

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