Article: Intussusception Among Recipients of Rotavirus Vaccine - United States, 1998-1999.(Statistical Data Included)

on August 31, 1998, a tetravalent rhesus-based rotavirus vaccine (RotaShield(R) [*], Wyeth Laboratories, Inc., Marietta, Pennsylvania) (RRV-TV) was licensed in the United States for vaccination of infants. The Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics, and the American Academy of Family Physicians have recommended routine use of RRV-TV for vaccination of healthy infants (1,2). During September 1, 1998-July 7, 1999, 15 cases of intussusception (a bowel obstruction in which one segment of bowel becomes enfolded within another segment) among infants who had received RRV-TV were reported to the Vaccine Adverse Event Reporting ...

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