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Article: DCs Are Susceptible to Infection.
- Article from:
- Blood Weekly
- Article date:
- July 12, 1999
- Author:
CopyrightCOPYRIGHT 1999 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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(CW HENDERSON PUBLISHER www.newsfile.com) -- Human T-lymphotropic virus type 1 may be able to infect dendritic cells in vivo, recent findings suggest.
Human dendritic cells (DCs) already are known to be susceptible to infection with various viruses, including measles virus, HIV-1, and influenza virus.
The development of human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is closely associated with the activation of T cells which are HTLV-1 specific but may cross-react with neural antigens (Ags), noted Masahiko Makino and colleagues of Japan's Kagoshima University ("The Role of Human T-Lymphotropic ...