Article: Antidepressants for General Anxiety Disorder.

ABSTRACT & COMMENTARY

Synopsis: This multicenter, randomized, double-blind, placebo-controlled study found the antidepressant venlafaxine (Effexor XR) to be effective, safe, and well-tolerated treatment for generalized anxiety disorder, even in the absence of depression.

Source: Davidson JRT, et al. J Clin Psychiatry 1999;60(8):528-535.

THIS STUDY COMPARES VENLAFAXINE (EFFEXOR XR) with buspirone (Buspar) and placebo in the treatment of general anxiety disorder (GAD) without comorbid major depression. Venlafaxine is believed to work by inhibiting both the serotonin and norepinephrine reuptake pumps. It is currently indicated for the treatment of ...

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