Article: Reversible Alteration of Morphology in an Invertebrate Erythrocyte: Properties of the Natural Inducer and the Cellular Response.

WILLIAM D. COHEN [*]

Department of Biological Sciences, Hunter College of CUNY, 695 Park Ave., New York, New York 10021; and Marine Biological Laboratory, Woods Hole, Massachusetts 02543

Abstract. The normal shape of the erythrocytes of the bivalves known as blood clams is maintained by a marginal band (MB) of microtubules. When hemolymph (or "blood") is withdrawn from the animal, its erythrocytes change, within minutes, from the normal smooth-surfaced, flattened ellipsoids (N-cells) to spheroids with folded surfaces (X-cells). This alteration can be prevented by rapidly diluting the hemolymph with physiological medium, yielding N-cells for use in ...

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