Article: NIH Clinical Center study demonstrates dangerous interaction between St. John' wort and an HIV protease inhibitor.

M2 PRESSWIRE-11 February 2000-US DEPT OF HHS: NIH Clinical Center study demonstrates dangerous interaction between St. John' wort and an HIV protease inhibitor (C)1994-2000 M2 COMMUNICATIONS LTD

RDATE:11022000

Researchers at the National Institutes of Health Clinical Center have demonstrated that a widely used herbal product -- St. John's wort -- could significantly compromise the effectiveness of an antiviral drug often prescribed to treat HIV infection.

The findings are detailed in the Feb. 12 issue of "The Lancet". "When St. John's wort and the protease inhibitor indinavir are taken together, the levels of indinavir in the blood drop ...

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