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Article: A Prospective Study of New Infections with Herpes Simplex Virus Type 1 and Type 2.
- Article from:
- Internal Medicine Alert
- Article date:
- January 15, 2000
CopyrightCOPYRIGHT 2000 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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ABSTRACT & COMMENTARY
Synopsis: Nearly half of all newly acquired HSV-2 infections are asymptomatic. Asymptomatic infections are more common in men than in women.
Source: Langenberg AG, et al. N Engl J Med 1999;341:1432-1438.
THIS PROJECT WAS INITIALLY DEVELOPED TO STUDY the effectiveness of a vaccine for the prevention of herpes simplex virus (HSV) infection. The trial vaccine was found to be ineffective. However, Langenberg and colleagues determined that the participants were appropriate for a prospective study of infection with HSV types 1 and 2. The enrolled 2393 individuals who were seronegative for HSV-2, though 63% of the cohort had ...