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Article: Immune Responses Mediated Via Antigen-Presenting Cells.(Brief Article)(Statistical Data Included)
- Article from:
- Gene Therapy Weekly
- Article date:
- March 16, 2000
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2000 MAR 16 - (NewsRx.com) --
DNA-based vaccines induce Th1-biased immune responses mediated via action on professional antigen-presenting cells (APC) which up-regulate IL-12 production, reported researchers from Japan.
"The efficacy of DNA-based immunization in conferring protective immunity against certain microbial pathogens including human immunodeficiency virus type 1 (HIV-1) has been described," stated Y. Asakura and colleagues, Osaka University, Japan. "The potential advantage of DNA-based immunization over the traditional vaccines largely results from its capacity to efficiently induce Th1-biased immune responses against an encoded antigen."
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