Article: Antimicrobial resistance with streptococcus pneumoniae in the United States, 1997-98.(Statistical Data Included)

From November 1997 to April 1998, 1,601 clinical isolates of Streptococcus pneumoniae were obtained from 34 U.S. medical centers. The overall rate of strains showing resistance to penicillin was 29.5%, with 17.4% having intermediate resistance. Multidrug resistance, defined as lack of susceptibility to penicillin and at least two other non-[Beta]-lactam classes of antimicrobial drugs, was observed in 16.0% of isolates. Resistance to all 10 [Beta]-lactam drugs examined in this study was directly related to the level of penicillin resistance. Penicillin resistance rates were highest in isolates from middle ear fluid and sinus aspirates of children [is less than] 5 years of ...

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