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Article: Fish Oil Fatty Acid Can Prevent Toxicity.(docosahexaenoic acid can prevent cyclosporin-A toxicity)
- Article from:
- Immunotherapy Weekly
- Article date:
- May 28, 2000
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2000 MAY 28 - (NewsRx.com) --
Docosahexaenoic acid (DHA), a fatty acid derived from fish oil, can mitigate the toxicity caused by cyclosporin-A (CsA) as long as it is in a non-oxidized state, according to researchers at the University of Louisville, Kentucky.
Cyclosporin-A, a compound derived from a fungus, is used to help prevent rejection of transplanted organs.
"The use of a fish oil vehicle for cyclosporin A (CsA) can decrease the toxic effects of CsA but the mechanism is unclear," explained W.D. Ehringer and colleagues in their report ("Docosahexaenoic acid reverses cyclosporin A-induced changes in membrane structure and function," ...