Article: PathoGenesis Corp. Begins Clinical Trial Of TOBI in Cystic Fibrosis Patients With Mild Lung Disease.

SEATTLE, May 30 /PRNewswire/ --

PathoGenesis Corp. (Nasdaq: PGNS) has begun to enroll patients in an open-label, randomized Phase IV clinical trial of TOBI(R) (tobramycin solution for inhalation) in cystic fibrosis patients with mild lung disease.

PathoGenesis plans to enroll up to 400 people, ages 6-15, who have cystic fibrosis (CF) and Pseudomonas aeruginosa lung infections but who have not yet experienced a major decline in lung function. At the beginning of the trial, patients' pulmonary function will be 70 percent to 90 percent of normal levels, as defined by forced expiratory volume at one second (FEV1). The 14-month study will compare patients ...

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