Article: GENENTECH'S TNKASE APPROVED; BLA SUBMITTED FOR ALLERGY DRUG.

Genentech Inc.'s stock rose 18 percent Monday with news that the FDA approved for marketing the thrombolytic agent TNKase and with the company's regulatory submission for its anti-IgE asthma and allergy drug.

The stock (NASDAQ:DNA) closed at $128.56, up $19.437.

TNKase (tenecteplase) is indicated to treat acute myocardial infarction (AMI) and has the potential to cannibalize Genentech's Activase, analysts said.

Anti-IgE is a recombinant humanized monoclonal antibody to immunoglobulin E being developed jointly by South San Francisco- based Genentech, East Hanover, N.J.-based Novartis Pharmaceuticals Corp., and Houston-based Tanox Inc. as a ...

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