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Article: The Contribution of Benzene to Smoking-Induced Leukemia.
- Article from:
- Environmental Health Perspectives
- Article date:
- April 1, 2000
- Author:
CopyrightCOPYRIGHT 2000 National Institute of Environmental Health Sciences. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Cigarette smoking is associated with an increased risk of leukemia; benzene, an established leukemogen, is present in cigarette smoke. By combining epidemiologic data on the health effects of smoking with risk assessment techniques for low-dose extrapolation, we assessed the proportion of smoking-induced total leukemia and acute myeloid leukemia (AML) attributable to the benzene in cigarette smoke. We fit both linear and quadratic models to data from two benzene-exposed occupational cohorts to estimate the leukemogenic potency of benzene. Using multiple-decrement life tables, we calculated lifetime risks of total leukemia and AML deaths for never, light, and heavy smokers. ...
Related newspaper, magazine, and journal articles:
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Article: Biggest benzene risks hide close to home.
Science News;
October 14, 1989 ;
700+ words
... ... that personal exposures to benzene generally do not correlate ... inhale about 600 micrograms of benzene daily--36 times as much ... nonsmoker unintentionally inhaling cigarette smoke. Wallace says his data suggest ... entire nationwide exposure to benzene results from smoking tobacco ...
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