Article: Clindamycin-Benzoyl Peroxide Combination May Offer Some Advantages in Acne Vulgaris.

SAN FRANCISCO -- Treating acne vulgaris with a combination of benzoyl peroxide plus clindamycin appeared to have some advantages over benzoyl peroxide monotherapy in three separate randomized, controlled studies that produced somewhat conflicting results.

In all three multicenter studies, the combination gel reduced inflammatory lesions to a greater extent than did the gel's individual components, investigators reported in poster presentations at the annual meeting of the American Academy of Dermatology.

In reducing the number of comedones, however, the effects of combination therapy and benzoyl peroxide monotherapy did not differ significantly.

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