Article: Neural stem cells can differentiate into mature neurons in regions of cerebral cortex, study finds.(Brief Article)

In mice, neural stem cells can be made to differentiate into mature neurons in regions of the cerebral cortex that normally do not undergo neurogenesis, according to a report in the June issue of Nature. These findings support the belief that under precisely the right conditions, the human cortex can regenerate neurons in response to injury or degeneration.

"What we did in this experiment was to see if we could induce signals that would recruit the precursors [stem cells] right in the brain where they are, without transplantation, to make new neurons in the cerebral cortex," said lead investigator Jeffrey Macklis, PhD from Harvard University Medical School in ...

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