Article: Outbreak among drug users caused by a clonal strain of group A streptococcus.

We describe an outbreak among drug users of severe soft-tissue infections caused by a clonal strain of group A streptococcus of M-type 25. Cases (n = 19) in drug users were defined as infections (mainly needle abscesses) due to the outbreak strain. Comparison with controls showed that infected drug users bought drugs more often at a specific place. Drug purchase and use habits may have contributed to this outbreak.

In the 1980s, reemergence of severe group A streptococcus (GAS) infections, especially toxic shock syndrome, necrotizing fasciitis, and bacteremia associated with high death rates, was observed (1,2). Temporal and geographic clustering of cases with severe ...

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