Article: "Mast Cell Disorder to be Ruled Out in MCS".

To the editor.--"Mast Cell Disorder to be Ruled Out in MCS." I make reference to the "1999 Consensus Statement" on Multiple Chemical Sensitivities (MCS),[1] which was also signed by me. In this statement, mastocytosis and porphyria are excluded from a diagnosis of MCS. However, in that statement, we are not instructed to rule out these diseases in every case that presents with chemical sensitivity nor are guidelines given as to the steps necessary to diagnose these diseases.

In 1996, I postulated that chemical exposure can trigger a mast cell disorder, which in turn can explain the mechanism of MCS.[2] Subsequently, I have studied 38 patients with a history of ...

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