Article: Repeat Courses of Prenatal Steroids Not Supported.(Brief Article)

Clinical trial data still 3-5 years away.

BETHESDA, M.D. -- Multiple courses of prenatal corticosteroids should not be given to women at risk for preterm delivery except as part of a clinical trial, a consensus development panel convened by the National Institutes of Health concluded.

The available data--consisting largely of studies that are small, retrospective, or hampered by methodologic inconsistencies--do not conclusively prove that routine repeat or rescue courses of steroids can either benefit or harm the mother and fetus, according to a statement issued by the panel.

Until data from a clinical trial show a favorable risk-benefit ratio, ...

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