|
|
Article: Cre-loxP Hammerhead Ribozyme Inhibits HIV-1 Replication.
- Article from:
- Gene Therapy Weekly
- Article date:
- November 9, 2000
CopyrightCOPYRIGHT 2000 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
2000 NOV 9 - (NewsRx.com) --
Researchers in Japan report that the Cre-loxP hammerhead ribozyme can inhibit HIV-1 replication.
"An alternative strategy has been the use of antiviral genes that are delivered to uninfected cells as either RNA or DNA and provide intercellular protection from HIV-1," stated Y. Habu and colleagues from the Chiba Institute of Technology, Narashino. "Antiviral genes include those encoding antisense molecules, ribozymes, transdominant proteins, and intracellular antibodies."
Habu et al. presented data from their study at the XIV International Roundtable, Nucleosides, Nucleotides, and their Biological Applications, held ...