Article: Novel Lipopolysaccharide Vaccine Immunogenic in Rabbit Model.

2000 NOV 15 - (NewsRx.com) --

Preclinical data of a novel liposomal complete-core lipopolysaccharide (LPS) vaccine against numerous bacterial pathogens are encouraging.

"Low preoperative anti-endotoxin antibody levels have been shown to be an independent predictor of adverse outcome following cardiac surgery," stated Elliott Bennett-Guerrero and colleagues from Columbia University College, New York. "Our objective is to develop a prophylactic vaccine strategy that can be evaluated in surgical patients and other high-risk hospitalized patients."

Bennett-Guerrero et al. presented data from their study at the annual meeting of the American ...

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