Article: Estrogen receptors detected in bone cells.

Estrogen receptors detected in bone cells

For years, scientists have known that osteoporosis, or bone loss, parallets decreasing estrogen levels in postmenopausal women. Suspecting that estrogen directly controls the growth of bone, they have looed for estrogen receptors within bone cells, but to no avail. Now, two research teams using highly sensitive detection methods have discovered small numbers of estrogen-binding sites that are probably receptors within the nuclei of bone cells.

By revealing the likely mechanism of how estrogen regulates bone growth, "the findings provide a rationale for treating menopausal women with estrogen to prevent bone loss," ...

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