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Article: Pathologic Evaluation of Sentinel Lymph Nodes in Colorectal Carcinoma.
- Article from:
- Archives of Pathology & Laboratory Medicine
- Article date:
- December 1, 2000
- Author:
CopyrightCOPYRIGHT 2000 College of American Pathologists. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Colorectal carcinoma remains a significant cause of morbidity and mortality worldwide, with global estimates of 783 000 new cases and 437000 deaths in 1990.[1] In the United States, colorectal carcinoma is the third most common cancer in both men and women, and is the fourth most common cancer overall, with 129400 new cases and 56 600 deaths estimated for 1999.[2]
The prognosis of colorectal carcinoma is greatly influenced by the stage of the disease at the time of diagnosis. Despite the more favorable prognosis of patients with localized cancer and no regional lymph node metastasis, up to 20% to 30% of patients will develop recurrent disease, despite apparent ...