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Article: Cholesterol Granulomas of the Lungs Associated With Microangiopathic Hemolytic Anemia and Thrombocytopenia in Pulmonary Hypertension: A Case Report and Review of the Literature.
- Article from:
- Archives of Pathology & Laboratory Medicine
- Article date:
- December 1, 2000
- Author:
CopyrightCOPYRIGHT 2000 College of American Pathologists. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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A Case Report and Review of the Literature
Cholesterol granulomas of the lungs are rare lesions of unknown cause but with characteristic morphologic features. There are few reports of these lesions in pulmonary disorders unrelated to endogenous lipoid pneumonia, pulmonary alveolar proteinosis, or cholesterol pneumonia. We found 27 such reported cases, and in 26 the cholesterol granulomas were associated with pulmonary hypertension (Table). More than 30 years ago, pulmonary parenchymal cholesterol granulomas were reported in 12 patients with known pulmonary hypertension,[1] with the conclusion that severe increase in pulmonary blood pressure was most important in ...