Article: Glaxo withdraws Lotronex under pressure.(FDA pressures Glaxo Wellcome to withdraw irritable bowel syndrome medication)(Brief Article)

On the brink of a decision to take its controversial irritable bowel syndrome drug Lotronex direct-to-consumer as part of a unique risk-management plan, Glaxo Wellcome in December withdrew the product from the marker under FDA pressure. After a tense, two-hour meeting with the agency in Washington on November 28, Glaxo issued a statement saying: "While the company disagrees with the FDAs assessment of the safety profile of the product, Glaxo Wellcome will cease distribution of Lotronex immediately." In a talk paper, the FDA said it presented Glaxo with new risk management options for Lotronex "that included restricting distribution of the drug or marketing withdrawal." It ...

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