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Article: Post-Grafting Telomere Loss Not Significant.
- Article from:
- Blood Weekly
- Article date:
- February 15, 2001
CopyrightCOPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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2001 FEB 15 - (NewsRx.com & NewsRx.net) --
- by Michael Greer, staff medical writer -- Telomere shortening observed after stem cell transplantation is limited to a relatively brief period after the procedure and should have little if any clinical impact, a new study suggests.
"Telomeres are specialized structures at the end of eukaryotic chromosomes that, in vertebrates, consist of hundreds to thousands of tandem repeats of the sequence TTAGGG," explained Nathalie Rufer and colleagues in the online edition of the journal Blood. "Because telomere length decreases with the number of cell divisions in vitro and with aging in vivo...short telomeres might ...