|
|
Article: Synthetic Gene Delivery Safely Targets Vascular Smooth Muscle Cells.
- Article from:
- Blood Weekly
- Article date:
- February 22, 2001
CopyrightCOPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
2001 FEB 22 - (NewsRx.com & NewsRx.net) --
by Michelle Marble, staff medical writer -- Synthetic peptide vectors may be a safe way to deliver therapeutic genes to help prevent allograft rejection.
"Chronic rejection is now the major cause of allograft failure," wrote J.M. Li and colleagues, University of London King's College Hospital. "A prominent characteristic of the histopathology is extensive intimal proliferation of vascular smooth muscle cells. Targeting vascular smooth muscle cells by gene therapy techniques offers a possible avenue for arresting or reversing chronic rejection." Li et al. published the results of their study in the journal ...