Article: How It All Starts Inside Your Brain: Science: New research on how cocaine, heroin, alcohol and amphetamines target neuronal circuits is revealing the biological basis of addiction, tolerance, withdrawal and relapse.(Special Report)

One by one, each crack addict took his turn in the fMRI tube, its magnets pounding away with a throbbing bass. A mirror inside was angled just so, allowing the addict to see a screen just outside the tube. Then the 10-minute video rolled. For two minutes, images of monarch butterflies flitted by; the fMRI, which detects active regions in the brain, saw nothing untoward. Then the scene shifted. Men ritualistically cooked crack... an addict handed cash to a pusher... users smoked. It was as if a neurological switch had been thrown: seeing the drug scenes not only unleashed in the addicts a surge of craving for crack, but also triggered visible changes in their brains as ...

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