|
|
Article: Role of sodium channel inhibition in neuroprotection: effect of vinpocetine.(on regional cerebral blood flow)
- Article from:
- Alternative Medicine Review
- Article date:
- February 1, 2001
- Author:
CopyrightCOPYRIGHT 2001 Thorne Research Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
Role of sodium channel inhibition in neuroprotection: effect of vinpocetine. Bonoczk P, Gulyas B, Adam-Vizi V, et al. Brain Res Bull 2000;53:245-254.
Vinpocetine (ethyl apovincaminate) discovered during the late 1960s has successfully been used in the treatment of central nervous system disorders of cerebrovascular origin for decades. The increase in the regional cerebral blood flow in response to vinpocetine administration is well established and strengthened by new diagnostical techniques (transcranial Doppler, near infrared spectroscopy, positron emission tomography). The latest in vitro studies have revealed the effect of the compound on Ca(2+)/calmodulin ...